Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Inpp4awbl
Name:	inositol polyphosphate-4-phosphatase, type I; weeble
MGI ID:	MGI:1934584
Gene:	Inpp4a  Location: Chr1:37338946-37449817 bp, + strand  Genetic Position: Chr1, 15.46 cM
Alliance:	Inpp4awbl page

Strain of Origin:

C57BL/6J-Aw

Allele Type:    Spontaneous Mutation:    Intragenic deletion   Mutation details: The underlying mutation underlying this allele was determined to be a single nucleotide deletion (G at nucleotide position 744). The resulting frameshift creates a stop codon at amino acid position 263, truncating most of the 939 amino acid protein including the active site. (J:72427) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Inpp4a Mutation:	55 strains or lines available

Original:	J:72427 Nystuen A, et al., A null mutation in inositol polyphosphate 4-phosphatase type I causes selective neuronal loss in weeble mutant mice. Neuron. 2001 Oct 25;32(2):203-12
All:	6 reference(s)