Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Crebbptm1Dli
Name:	CREB binding protein; targeted mutation 1, David Livingston
MGI ID:	MGI:1926888
Synonyms:	CBP-
Gene:	Crebbp  Location: Chr16:3899198-4031864 bp, - strand  Genetic Position: Chr16, 2.4 cM
Alliance:	Crebbptm1Dli page

Germline Transmission:	Earliest citation of germline transmission: J:60630
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Replacement of two exons encoding the CH1 domain of the Crebbp gene with a neomycin cassette. (J:60630)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

List all tumor models in MMHCdb carrying Crebbptm1Dli

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Crebbp Mutation:	99 strains or lines available

Original:	J:60630 Kung AL, et al., Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP. Genes Dev. 2000 Feb 1;14(3):272-7
All:	11 reference(s)