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Gkn3 Gene Detail
Summary
  • Symbol
    Gkn3
  • Name
    gastrokine 3
  • Synonyms
    1190003M12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916138
    NCBI Gene: 68888
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:87360301-87365917 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 37.96 cM, cytoband D2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    58 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916138
protein coding gene Chr6:87360238-87365917 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030991
protein coding gene Chr6:88735340-88741016 (-)
A/J MGP_AJ_G0030957
protein coding gene Chr6:85303423-85309193 (-)
AKR/J MGP_AKRJ_G0030888
protein coding gene Chr6:87773752-87779423 (-)
BALB/cJ MGP_BALBcJ_G0030970
protein coding gene Chr6:85305860-85311531 (-)
C3H/HeJ MGP_C3HHeJ_G0030740
protein coding gene Chr6:96699726-96705396 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031427
protein coding gene Chr6:91120815-91126486 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028611
protein coding gene Chr6:83487258-83493066 (-)
CAST/EiJ MGP_CASTEiJ_G0030079
protein coding gene Chr6:87845440-87852524 (-)
CBA/J MGP_CBAJ_G0030654
protein coding gene Chr6:94660939-94666722 (-)
DBA/2J MGP_DBA2J_G0030810
protein coding gene Chr6:84609150-84614827 (-)
FVB/NJ MGP_FVBNJ_G0030763
protein coding gene Chr6:83789861-83795825 (-)
LP/J MGP_LPJ_G0030887
protein coding gene Chr6:88746680-88752355 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030796
protein coding gene Chr6:98776625-98782308 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031454
protein coding gene Chr6:87616637-87622314 (-)
PWK/PhJ MGP_PWKPhJ_G0029794
protein coding gene Chr6:83572730-83578409 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029622
protein coding gene Chr6:86434336-86441885 (-)
WSB/EiJ MGP_WSBEiJ_G0030160
protein coding gene Chr6:88074791-88081149 (-)



Homology
more
  • Human Ortholog
    GKN3P, gastrokine 3, pseudogene
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GKN3P, gastrokine 3, pseudogene
  • Links
    NCBI Gene ID: 100132413
    UniProt: P0CG01

  • Chr Location
    2p13.3; chr2:68921248-68926834 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68888 NCBI Gene Model | MGI Sequence Detail 5617 C57BL/6J ±  kb
transcript NM_026860 RefSeq | MGI Sequence Detail 793 Not Specified  
polypeptide Q9D0T7 UniProt | EBI | MGI Sequence Detail 191 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:331053 Chandrasekaran P, et al., CXCL12 defines lung endothelial heterogeneity and promotes distal vascular growth. Development. 2022 Nov 1;149(21):dev200909

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory