Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Mdm4Gt(VICTR20)7Lex
Name:	transformed mouse 3T3 cell double minute 4; gene trap 7, Lexicon Genetics
MGI ID:	MGI:1861977
Synonyms:	Mdm4-null, Mdm4tm1Lex, mdmx1
Gene:	Mdm4  Location: Chr1:132913843-132958325 bp, - strand  Genetic Position: Chr1, 57.75 cM, cytoband G-G
Alliance:	Mdm4Gt(VICTR20)7Lex page

Germline Transmission:	Earliest citation of germline transmission: J:77907
Parent Cell Line:	Lex-1 (ES Cell)
Strain of Origin:	129S5/SvEvBrd
Project Collection:	Lexicon

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector   Mutation details: The gene trap vector insertion is near the 5'-end of the coding region of the gene, 1-2 codons downstream of the ATG start site. (J:77030)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

List all tumor models in MMHCdb carrying Mdm4Gt(VICTR20)7Lex

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mdm4 Mutation:	191 strains or lines available

Original:	J:46940 Zambrowicz BP, et al., Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells. Nature. 1998 Apr 9;392(6676):608-11
All:	10 reference(s)