Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Inpp5dtm1Dmt
Name:	inositol polyphosphate-5-phosphatase D; targeted mutation 1, Dan Dumont
MGI ID:	MGI:1861956
Synonyms:	Ship -, SHIP-1-, SHIP1-
Gene:	Inpp5d  Location: Chr1:87548034-87648229 bp, + strand  Genetic Position: Chr1, 44.44 cM, cytoband C5
Alliance:	Inpp5dtm1Dmt page

Germline Transmission:	Earliest citation of germline transmission: J:72477
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     A neomycin resistance cassette replaced all of exon 1 and part of intron 1. (J:72477)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Inpp5d Mutation:	93 strains or lines available

Original:	J:72477 Liu Q, et al., The inositol polyphosphate 5-phosphatase ship is a crucial negative regulator of B cell antigen receptor signaling. J Exp Med. 1998 Oct 5;188(7):1333-42
All:	23 reference(s)