Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cnga2tm1Ngai
Name:	cyclic nucleotide gated channel alpha 2; targeted mutation 1, John Ngai
MGI ID:	MGI:1861912
Synonyms:	CNG channel alpha -
Gene:	Cnga2  Location: ChrX:71035455-71053824 bp, + strand  Genetic Position: ChrX, 37.15 cM, cytoband A6
Alliance:	Cnga2tm1Ngai page

Germline Transmission:	Earliest citation of germline transmission: J:36286
Parent Cell Line:	W9.5/W95 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin selection cassette replaced a genomic fragment containing the sequences encoding the fifth membrane-spanning region, the pore-forming region, the sixth membrane-spanning region and a portion of the carboxy-terminal tail. (J:36286, J:96894)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cnga2 Mutation:	15 strains or lines available

Original:	J:36286 Brunet LJ, et al., General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel. Neuron. 1996 Oct;17(4):681-93
All:	13 reference(s)