Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol: Lrp6Cd Name: low density lipoprotein receptor-related protein 6; crooked MGI ID: MGI:1861309 Synonyms: crooked tail Gene: Lrp6  Location: Chr6:134423439-134543876 bp, - strand  Genetic Position: Chr6, 65.37 cM Alliance: Lrp6Cd page

Skeletal abnormalities of the Lrp6Cd/Lrp6Cd mouse Show the 2 phenotype image(s) involving this allele.

Strain of Origin:

A

Allele Type:    Spontaneous Mutation:    Nucleotide substitutions   Mutation details: A single nucleotide substitution was found in exon 7 which results in a G494D conversion in the second YWTD-EGF repeat domain. (J:101423) Inheritance:    Semidominant

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	20 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lrp6 Mutation:	95 strains or lines available

Original:	J:13045 Morgan WC, A new crooked tail mutation involving distinctive pleiotropism. J Genet. 1954;52(2):354-373
All:	10 reference(s)