Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pik3cgtm1Dwu
Name:	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; targeted mutation 1, Dianqing Wu
MGI ID:	MGI:1858011
Synonyms:	p110gamma-, PI3Kgamma-
Gene:	Pik3cg  Location: Chr12:32223472-32258658 bp, - strand  Genetic Position: Chr12, 13.74 cM, cytoband B
Alliance:	Pik3cgtm1Dwu page

Germline Transmission:	Earliest citation of germline transmission: J:60348
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: A part of the first exon and the entire second and third exons were replaced by a GFP gene, which was fused in-frame to the coding sequence of Pik3cg. GFP is expressed under the control of Pik3cg promoter elements in this allele. (J:60348)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pik3cg Mutation:	59 strains or lines available

Original:	J:60348 Li Z, et al., Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction [see comments]. Science. 2000 Feb 11;287(5455):1046-9
All:	19 reference(s)