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Rab3atm1Sud
Targeted Allele Detail
Summary
Symbol: Rab3atm1Sud
Name: RAB3A, member RAS oncogene family; targeted mutation 1, Thomas C Sudhof
MGI ID: MGI:1857240
Synonyms: Rab3a-
Gene: Rab3a  Location: Chr8:71207328-71211323 bp, + strand  Genetic Position: Chr8, 34.15 cM
Alliance: Rab3atm1Sud page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64297
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin cassette replaced the promoter and the first two exons of the gene. Western blots of brain extracts did not detect any encoded protein in homozygous mice. (J:64297)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Rab3a Mutation:  14 strains or lines available
References
Original:  J:64297 Geppert M, et al., The role of Rab3A in neurotransmitter release. Nature. 1994 Jun 9;369(6480):493-7
All:  33 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory