Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fostm1Pa
Name:	FBJ osteosarcoma oncogene; targeted mutation 1, Virginia E Papaioannou
MGI ID:	MGI:1857171
Synonyms:	c-fos-
Gene:	Fos  Location: Chr12:85520664-85524047 bp, + strand  Genetic Position: Chr12, 39.7 cM
Alliance:	Fostm1Pa page

Germline Transmission:	Earliest citation of germline transmission: J:3233
Parent Cell Line:	PJ5 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: Exon 1 was disrupted by the insertion of a neomycin selection cassette. Northern blot analysis showed an absence of transcript in homozygous mutant mice. (J:70953)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

10 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Fos Mutation:	42 strains or lines available

Original:	J:3233 Johnson RS, et al., Pleiotropic effects of a null mutation in the c-fos proto-oncogene. Cell. 1992 Nov 13;71(4):577-86
All:	32 reference(s)