Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Otop1tlt
Name:	otopetrin 1; tilted
MGI ID:	MGI:1856638
Synonyms:	tilted head, tlt
Gene:	Otop1  Location: Chr5:38434748-38461560 bp, + strand  Genetic Position: Chr5, 20.35 cM
Alliance:	Otop1tlt page

Strain of Origin:

STOCK Oca2p-6H/Oca2p-d

Allele Type:    Spontaneous Mutation:    Single point mutation   Mutation details: The mutation in the tlt mouse has been identified as a C-to-A transversion at coding nucleotide 452 in the third exon of the gene. This results in a alanine to glutamic acid change at amino acid position 151 (p.A151E). (J:82639) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Otop1 Mutation:	38 strains or lines available

Original:	J:30803 Lane PW, Tilted (tlt). Mouse News Lett. 1986;75:28
All:	17 reference(s)