Gdf5<bp-3J> Spontaneous Allele Detail MGI Mouse (MGI:1856340)

Gdf5^bp-3J
Spontaneous Allele Detail

Summary

Symbol:	Gdf5^bp-3J
Name:	growth differentiation factor 5; brachypodism 3 Jackson
MGI ID:	MGI:1856340
Gene:	Gdf5 Location: Chr2:155782943-155787204 bp, - strand Genetic Position: Chr2, 77.26 cM
Alliance:	Gdf5^bp-3J page

Mutation
origin

Strain of Origin:

BALB/cJ

Mutation
description

Allele Type:		Spontaneous
Mutation:		Intragenic deletion
		Mutation details: A CG dinucleotide was replaced by a single base pair (T) at position 876, causing a frame shift and a translational stop at the next codon. (J:17582)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	12 assay results
In Structures Affected by this Mutation:	11 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Gdf5 Mutation:	27 strains or lines available

Notes

The long bones of the limbs of mutant mice are slightly shorter than controls, and the fibula is shortened proximally. The bones of the axial skeleton are unaffected.

References

Original:	J:16313 Sweet HO, Remutations at The Jackson Laboratory. Mouse Genome. 1993;91(4):862-65
All:	8 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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