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Tyrc-p
Spontaneous Allele Detail
Summary
Symbol: Tyrc-p
Name: tyrosinase; platinum
MGI ID: MGI:1855981
Synonyms: cP
Gene: Tyr  Location: Chr7:87073979-87142637 bp, - strand  Genetic Position: Chr7, 49.01 cM
Alliance: Tyrc-p page
Mutation
origin
Strain of Origin:  DBA/2J
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
 
Mutation detailsThe mutation in the platinum allele was found to be an A-to-T substitution, changing a lysine residue at position 507 or 489 to a termination codon (p.K507* for pre-protein, p.K489* for mature protein). (J:30177)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tyr Mutation:  373 strains or lines available
References
Original:  J:13442 Dickie MM, Platinum. Mouse News Lett. 1966;34:30
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory