Gene Expression Data
Assay Details
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Assay
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Reference:
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J:55705
Nardelli J, et al., Expression and genetic interaction of transcription factors GATA-2 and GATA-3 during development of the mouse central nervous system. Dev Biol. 1999 Jun 15;210(2):305-21
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1342741
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Gene symbol:
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Isl1
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Gene name:
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ISL1 transcription factor, LIM/homeodomain
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Probe:
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Isl-1 probe-3
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
2.H:
embryonic day 11.5
(more  )
Specimen
2.H:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: future spinal cord |
Present |
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2H
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Rostrally to r4, expression is restricted mainly to the common oculomotor, trochlear, and trigeminal nuclei. Stong expression is seen in neurons of the presumptive facial motor nucleus and in the longitudinal column of motor neuron precursers.
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Specimen
8.A:
embryonic day 10.5
(more )
Specimen
8.A:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
8.E:
(close )
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Genetic Background:
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involves: 129S4/SvJae
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Mutant Allele(s):
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Gata2tm1Sho/Gata2tm1Sho
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: future spinal cord |
Present |
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8E
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Expression appears to be activated at much lower levels in the ventral hindbrain and spinal cord of the mutant.
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| TS17: hindbrain |
Present |
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8E
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Expression appears to be activated at much lower levels in the ventral hindbrain and spinal cord of the mutant.
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Analysis Tools