About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:50462 Dassule HR, et al., Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth. Dev Biol. 1998 Oct 15;202(2):215-27
Assay type: RNA in situ
MGI Accession ID: MGI:1340492
Gene symbol: Wnt10a
Gene name: wingless-type MMTV integration site family, member 10A
Probe: Wnt10a probe1
Probe preparation: RNA
Results
Specimen 1A: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: 1st branchial arch mandibular component Absent 1A
TS18: tongue Absent 1A
Specimen 1G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: mandible primordium Present Regionally restricted 1G Highest levels of expression are mesially and distally with an apparent downregulation in between.
TS19: tongue Absent 1G
Specimen 1M: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: mandible primordium Present Regionally restricted 1M Expression is completely downregulated in diastema. Expression occurs at midline in incisor domains and further distally in molar primordia. Double in situs of Wnt10a/Shh and Wnt10b/Shh confirm expression in either the same or intermixed cell populations.
TS20: tongue Absent 1M
Specimen 1S: embryonic day 12.0 (more )
Note: Tissue was embedded in 30% BSA, 0.49% gelatin, 20% sucrose in PBS and crosslinked with glutaraldehyde.
Structure Level Pattern Image Note
TS20: mandible primordium Weak Regionally restricted 1S Wnt10a is expressed at the tip of the tooth epithelium.
Specimen 2A: embryonic day 13.5 (more )
Note: Bud stage. Tissue was embedded in 30% BSA, 0.49% gelatin, 20% sucrose in PBS and crosslinked with glutaraldehyde.
Structure Level Pattern Image Note
TS21: lower jaw molar epithelium Strong Regionally restricted 2A Wnt10a is strongly expressed at the tip of the invaginating epithelium.
Specimen 2B: embryonic day 14.5 (more )
Note: Cap stage. Tissue was embedded in 30% BSA, 0.49% gelatin, 20% sucrose in PBS and crosslinked with glutaraldehyde.
Structure Level Pattern Image Note
TS22: lower jaw incisor enamel organ Strong 2B Strongly expression in the enamel knot.
TS22: enamel knot Strong 2B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory