Fn1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:16247 George EL, et al., Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development. 1993 Dec;119(4):1079-91
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:1334399
Gene symbol:	Fn1
Gene name:	fibronectin 1

Antibody:	61.1
Detection system:	Secondary antibody coupled to fluorescein

Results

4A ©

Specimen 4A: embryonic day 7.5 (more

)
Note: This is a sagittal section.

Structure	Level	Pattern	Image	Note
TS11: embryo	Present	Regionally restricted	4A	Expression is between all three germ layers, and among mesodermal layers. Expression is also detected between the cell layers in the amnion and the yolk sac.

4B ©

Specimen 4B: embryonic day 7.5; Fn1^tm1Hyn/Fn1^tm1Hyn (more

)
Note: This is a sagittal section.

Structure	Level	Pattern	Image	Note
TS11: embryo	Absent		4B

4D ©

Specimen 4D: embryonic day 7.5 (more

)
Note: This is a transverse section.

Structure	Level	Pattern	Image	Note
TS11: embryo	Present	Regionally restricted	4D	Expression is between all three germ layers, and among mesodermal layers. Expression is also detected between the cell layers in the amnion and the yolk sac.

4E ©

Specimen 4E: embryonic day 7.5; Fn1^tm1Hyn/Fn1^tm1Hyn (more

)
Note: This is a transverse section.

Structure	Level	Pattern	Image	Note
TS11: embryo	Absent		4E

5A/C ©

Specimen 5A/C: embryonic day 8.0 (more

)
Note: A is a mid-sagittal section and B is a para-sagittal section.

Structure	Level	Pattern	Image	Note
TS12: 1st branchial arch mesenchyme derived from head mesoderm	Present		5A/C
TS12: head somite	Present	Regionally restricted	5A/C	Expression surrounds the somites.
TS12: trunk somite	Present	Regionally restricted	5A/C	Expression surrounds the somites.
TS12: allantois	Present	Regionally restricted	5A/C	Expression is between the cell layers of the amnion and within the allantois and blood islands of the yolk sac.
TS12: amnion	Present	Regionally restricted	5A/C	Expression is between the cell layers of the amnion and within the allantois and blood islands of the yolk sac.
TS12: blood island	Present	Regionally restricted	5A/C	Expression is between the cell layers of the amnion and within the allantois and blood islands of the yolk sac.

5B/D ©

Specimen 5B/D: embryonic day 8.0 (more

)

Structure	Level	Pattern	Image	Note
TS12: 1st branchial arch mesenchyme derived from head mesoderm	Present		5B/D
TS12: head somite	Present	Regionally restricted	5B/D	Expression surrounds the somites.
TS12: trunk somite	Present	Regionally restricted	5B/D	Expression surrounds the somites.
TS12: allantois	Present	Regionally restricted	5B/D	Expression is between the cell layers of the amnion and within the allantois and blood islands of the yolk sac.
TS12: amnion	Present	Regionally restricted	5B/D	Expression is between the cell layers of the amnion and within the allantois and blood islands of the yolk sac.
TS12: blood island	Present	Regionally restricted	5B/D	Expression is between the cell layers of the amnion and within the allantois and blood islands of the yolk sac.

7A ©

Specimen 7A: embryonic day 8.5 (more

)

Structure	Level	Pattern	Image	Note
TS13: 1st branchial arch mesenchyme derived from head mesoderm	Present		7A
TS13: 2nd branchial arch mesenchyme derived from head mesoderm	Present		7A
TS13: dorsal aorta	Present	Regionally restricted	7A	Expression is surrounding these tissues.
TS13: head somite	Present	Regionally restricted	7A	Expression is surrounding these tissues.
TS13: neural tube	Present	Regionally restricted	7A	Expression is surrounding these tissues.
TS13: notochord	Present	Regionally restricted	7A	Expression is surrounding these tissues.
TS13: bulbus cordis caudal half endocardial tube	Present		7A
TS13: bulbus cordis rostral half endocardial tube	Present		7A
TS13: common atrial chamber endocardial tube	Present		7A
TS13: primitive ventricle endocardial tube	Present		7A
TS13: extraembryonic component	Present	Regionally restricted	7A	Expression is between the cell layers of the amnion and in the blood islands.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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