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Gene Expression Data
Assay Details
Assay
Reference: J:40390 Sasaki H, et al., A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro. Development. 1997 Apr;124(7):1313-22
Assay type: RNA in situ
MGI Accession ID: MGI:1332606
Gene symbol: Gli3
Gene name: GLI-Kruppel family member GLI3
Probe: Gli3 cDNA4
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 4E: embryonic day 8.5 (more )
Note: 9-11 somites.
Structure Level Pattern Image Note
TS13: neural tube floor plate Absent 4E
Specimen 4J: embryonic day 8.5 (more )
Note: 9-11 somites.
Structure Level Pattern Image Note
TS13: neural tube Strong Graded 4J In the anterior part, strong Gli3 expression is widely observed but in an opposite gradient to Gli- it is strong in the dorsal region and weak in ventral. Gli3 seems to be expressed at a very low level throughout the neural tube in the posterior part.
TS13: neural tube floor plate Absent 4J
Specimen 4O: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 4O Strong Gli3 expression is widely observed but in an opposite gradient to Gli, i.e. it is strong in the dorsal region and weak in ventral.
TS15: tail neural plate Present Regionally restricted 4O Strong Gli3 expression is widely observed but in an opposite gradient to Gli, i.e. it is strong in the dorsal region and weak in ventral.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory