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Gene Expression Data
Assay Details
Assay
Reference: J:38381 Mo R, et al., Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development. Development. 1997 Jan;124(1):113-23
Assay type: RNA in situ
MGI Accession ID: MGI:1327347
Gene symbol: Gli3
Gene name: GLI-Kruppel family member GLI3
Probe: pGli-3a
Probe preparation: Antisense RNA
Results
Specimen 10.5 p.c. embryo: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 5D Gli3 is broadly expressed in the undifferentiated mesenchyme. The zone of polarizing activity shows little or no expression.
Specimen 12.5 p.c. fore limb: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb interdigital region mesenchyme Present 5H
TS20: forelimb Present Regionally restricted 5H Gli3 is expressed in the mesenchyme surrounding the condensing mesenchyme.
TS20: foot Present 5H Gli3 is expressed at higher levels in the autopods.
TS20: hand Present 5H Gli3 is expressed at higher levels in the autopods.
Specimen 12.5 p.c. embryo: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb interdigital region mesenchyme Present 5J , 5L
TS20: hindlimb interdigital region mesenchyme Present 5J , 5L
TS20: forelimb Present Regionally restricted 5L
TS20: hindlimb Present Regionally restricted 5L
TS20: foot Strong 5L Gli3 is expressed at a higher level in the autopods.
TS20: hand Strong 5L Gli3 is expressed at a higher level in the autopods.
Specimen 11.5 p.c. embryo: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future spinal cord Present 5N , 5P
TS19: head mesenchyme Strong Regionally restricted 5N Gli3 is highly expressed in the developing facial mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/09/2024
MGI 6.23 		The Jackson Laboratory