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Zc3h11a Gene Detail
Summary
  • Symbol
    Zc3h11a
  • Name
    zinc finger CCCH type containing 11A
  • Synonyms
    1110003F06Rik, 5730454B08Rik, G630041M05Rik, mKIAA0663
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917829
    NCBI Gene: 70579
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:133547600-133589118 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 57.94 cM, cytoband E4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    178 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917829
 protein coding gene Chr1:133547600-133589137 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016489
 protein coding gene Chr1:137212699-137261706 (-)
A/J MGP_AJ_G0016472
 protein coding gene Chr1:132078157-132120544 (-)
AKR/J MGP_AKRJ_G0016438
 protein coding gene Chr1:136014070-136054246 (-)
BALB/cJ MGP_BALBcJ_G0016432
 protein coding gene Chr1:132411445-132454781 (-)
C3H/HeJ MGP_C3HHeJ_G0016258
 protein coding gene Chr1:136105061-136151088 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016893
 protein coding gene Chr1:142244163-142293574 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014604
 protein coding gene Chr1:125229325-125270678 (-)
CAST/EiJ MGP_CASTEiJ_G0015838
 protein coding gene Chr1:135145428-135189987 (-)
CBA/J MGP_CBAJ_G0016232
 protein coding gene Chr1:147137602-147179074 (-)
DBA/2J MGP_DBA2J_G0016337
 protein coding gene Chr1:131093664-131136307 (-)
FVB/NJ MGP_FVBNJ_G0016336
 protein coding gene Chr1:129713400-129756106 (-)
LP/J MGP_LPJ_G0016408
 protein coding gene Chr1:138498583-138543898 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016361
 protein coding gene Chr1:152881297-152934121 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016929
 protein coding gene Chr1:135723381-135770821 (-)
PWK/PhJ MGP_PWKPhJ_G0015624
 protein coding gene Chr1:130093992-130137698 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015411
 protein coding gene Chr1:134704443-134749817 (-)
WSB/EiJ MGP_WSBEiJ_G0015902
 protein coding gene Chr1:135750764-135797156 (-)



Homology
more
  • Human Ortholog
    ZC3H11A, zinc finger CCCH-type containing 11A
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZC3H11A, zinc finger CCCH-type containing 11A
  • Synonyms
    ZC3HDC11A
  • Links
    NCBI Gene ID: 9877
    neXtProt AC: NX_O75152
    UniProt: O75152

  • Chr Location
    1q32.1; chr1:203795623-203854999 (+)  GRCh38
  • Human Ortholog
    ZC3H11B, zinc finger CCCH-type containing 11B
  • Synonyms
    ZC3HDC11B
  • Links
    NCBI Gene ID: 643136
    UniProt: A0A1B0GTU1

  • Chr Location
    1q41; chr1:219608012-219613105 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    20 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    4
  • Tissues
    3
  • cDNA Data
    23
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000102976 Ensembl Gene Model | MGI Sequence Detail 41519 C57BL/6J ±  kb
    transcript ENSMUST00000191896 Ensembl | MGI Sequence Detail 4396 Not Applicable  
    polypeptide ENSMUSP00000141255 Ensembl | MGI Sequence Detail 792 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      9 Sequences
    • InterPro Domains
      IPR041686 Zinc-finger CCCH domain
      IPR000571 Zinc finger, CCCH-type
      IPR036855 Zinc finger, CCCH-type superfamily
    Molecular
    Reagents
    less
    • All nucleic 24
      cDNA 24

      Microarray probesets 12
    Other
    Accession IDs
    less
    MGI:1923538, MGI:2444045
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 2
      Gene Ontology 4
      Phenotypes 10
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345229 Bhattacharjee R, et al., Compromised transcription-mRNA export factor THOC2 causes R-loop accumulation, DNA damage and adverse neurodevelopment. Nat Commun. 2024 Feb 8;15(1):1210
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory