Compare GO annotations related to Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency using OMIM genes and OrthoDisease orthologs

A table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: mouse, human, rat, worm, fly, dicty, chicken, zfin, rice, tair, yeast, pombe, pfalc, and multiple.
Green arrows indicate "is_a"; Purple arrows indicate "part_of"
GO annotations: Mouse from MGI; Human from GO Annotations @ EBI (GOA); Rat from RGD; Chicken from GOA; Fly from FlyBase; Pfalc from PlasmoDB; Worm from WormBase; Dicty from dictyBase; Yeast from SGD; Zfin from ZFIN; Tair from TAIR/TIGR; Rice from Gramene; Pombe from Sanger GeneDB.
Does not include evidence codes: IEA, ISS, RCA, NR, ND, NAS, IC, IGC, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
All nodes are linked to the MGI GO browser.
Graph generated Fri Dec 7 14:03:29 2007.

Category	ID	Term	DB Object	Evidence	Organism	Reference
Molecular Function	GO:0043531	ADP binding	P48506	IDA	Human	PMID:24639
Molecular Function	GO:0050662	coenzyme binding	P48506	IPI	Human	PMID:9675072
Molecular Function	GO:0050662	coenzyme binding	P48506	IPI	Human	PMID:9841880
Molecular Function	GO:0016595	glutamate binding	P48506	IDA	Human	PMID:9841880
Molecular Function	GO:0004357	glutamate-cysteine ligase activity	MGI:104990	IDA	Mouse	MGI:MGI:2157601\|PMID:10966520
Molecular Function	GO:0004357	glutamate-cysteine ligase activity	MGI:104990	IDA	Mouse	MGI:MGI:2447526\|PMID:12384496
Molecular Function	GO:0004357	glutamate-cysteine ligase activity	MGI:104990	IDA	Mouse	MGI:MGI:3047441\|PMID:15288121
Molecular Function	GO:0004357	glutamate-cysteine ligase activity	MGI:104990	IDA	Mouse	MGI:MGI:3607629\|PMID:16081425
Molecular Function	GO:0004357	glutamate-cysteine ligase activity	MGI:104990	IMP	Mouse	MGI:MGI:1928560\|PMID:11118286
Molecular Function	GO:0004357	glutamate-cysteine ligase activity	P48506	IDA	Human	PMID:11972604
Molecular Function	GO:0004357	glutamate-cysteine ligase activity	P48506	IMP	Human	PMID:16183645
Molecular Function	GO:0004357	glutamate-cysteine ligase activity	P48506	IDA	Human	PMID:8104187
Molecular Function	GO:0004357	glutamate-cysteine ligase activity	S000003637	IDA	Yeast	SGD_REF:S000040589\|PMID:1687097
Molecular Function	GO:0004357	glutamate-cysteine ligase activity	S000003637	IMP	Yeast	SGD_REF:S000052673\|PMID:2184310
Molecular Function	GO:0000287	magnesium ion binding	P48506	IDA	Human	PMID:24639
Molecular Function	GO:0046982	protein heterodimerization activity	MGI:104990	IPI	Mouse	MGI:MGI:2447526\|PMID:12384496
Molecular Function	GO:0046982	protein heterodimerization activity	MGI:104990	IPI	Mouse	MGI:MGI:3607629\|PMID:16081425
Cellular Component	GO:0005829	cytosol	MGI:104990	IDA	Mouse	MGI:MGI:2447526\|PMID:12384496
Cellular Component	GO:0017109	glutamate-cysteine ligase complex	MGI:104990	IDA	Mouse	MGI:MGI:2447526\|PMID:12384496
Cellular Component	GO:0005622	intracellular	S000003637	IDA	Yeast	SGD_REF:S000052673\|PMID:2184310
Biological Process	GO:0006916	anti-apoptosis	P48506	IDA	Human	PMID:10439045
Biological Process	GO:0006534	cysteine metabolic process	P48506	IDA	Human	PMID:2294991
Biological Process	GO:0006536	glutamate metabolic process	P48506	IDA	Human	PMID:2294991
Biological Process	GO:0006536	glutamate metabolic process	P48506	IDA	Human	PMID:12663448
Biological Process	GO:0006750	glutathione biosynthetic process	MGI:104990	IMP	Mouse	MGI:MGI:1858542\|PMID:10805773
Biological Process	GO:0006750	glutathione biosynthetic process	MGI:104990	IDA	Mouse	MGI:MGI:3607629\|PMID:16081425
Biological Process	GO:0006750	glutathione biosynthetic process	P48506	IMP	Human	PMID:12663448
Biological Process	GO:0006750	glutathione biosynthetic process	P48506	IDA	Human	PMID:10395918
Biological Process	GO:0006750	glutathione biosynthetic process	P48506	IDA	Human	PMID:8104187
Biological Process	GO:0006750	glutathione biosynthetic process	S000003637	IDA	Yeast	SGD_REF:S000040589\|PMID:1687097
Biological Process	GO:0006750	glutathione biosynthetic process	S000003637	IMP	Yeast	SGD_REF:S000049527\|PMID:8768524
Biological Process	GO:0006749	glutathione metabolic process	MGI:104990	IMP	Mouse	MGI:MGI:1928560\|PMID:11118286
Biological Process	GO:0019852	L-ascorbic acid metabolic process	MGI:104990	IMP	Mouse	MGI:MGI:1928560\|PMID:11118286
Biological Process	GO:0043066	negative regulation of apoptosis	MGI:104990	IGI	Mouse	MGI:MGI:3047441\|PMID:15288121
Biological Process	GO:0031397	negative regulation of protein ubiquitination	MGI:104990	IMP	Mouse	MGI:MGI:3695876\|PMID:17189825
Biological Process	GO:0016481	negative regulation of transcription	P48506	IDA	Human	PMID:10439045
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	MGI:104990	IMP	Mouse	MGI:MGI:3695876\|PMID:17189825
Biological Process	GO:0050880	regulation of blood vessel size	P48506	IMP	Human	PMID:12598062
Biological Process	GO:0030503	regulation of cell redox homeostasis	P48506	IDA	Human	PMID:10439045
Biological Process	GO:0051900	regulation of mitochondrial depolarization	MGI:104990	IGI	Mouse	MGI:MGI:3047441\|PMID:15288121
Biological Process	GO:0046685	response to arsenic	MGI:104990	IMP	Mouse	MGI:MGI:3695876\|PMID:17189825
Biological Process	GO:0046686	response to cadmium ion	S000003637	IDA	Yeast	SGD_REF:S000059727\|PMID:10921921
Biological Process	GO:0046686	response to cadmium ion	S000003637	IEP	Yeast	SGD_REF:S000056170\|PMID:9044254
Biological Process	GO:0009409	response to cold	S000003637	IEP	Yeast	SGD_REF:S000073700\|PMID:12859956
Biological Process	GO:0042493	response to drug	S000003637	IMP	Yeast	SGD_REF:S000086944\|PMID:16234568
Biological Process	GO:0009408	response to heat	P48506	IDA	Human	PMID:8104187
Biological Process	GO:0009408	response to heat	S000003637	IEP	Yeast	SGD_REF:S000050112\|PMID:10809786
Biological Process	GO:0009725	response to hormone stimulus	P48506	IDA	Human	PMID:8104187
Biological Process	GO:0042542	response to hydrogen peroxide	S000003637	IMP	Yeast	SGD_REF:S000063336\|PMID:7615092
Biological Process	GO:0042542	response to hydrogen peroxide	S000003637	IEP	Yeast	SGD_REF:S000056170\|PMID:9044254
Biological Process	GO:0046689	response to mercury ion	S000003637	IEP	Yeast	SGD_REF:S000069228\|PMID:11816031
Biological Process	GO:0006979	response to oxidative stress	P48506	IDA	Human	PMID:11972604
Biological Process	GO:0006979	response to oxidative stress	P48506	IDA	Human	PMID:10395918
Biological Process	GO:0009410	response to xenobiotic stimulus	MGI:104990	IMP	Mouse	MGI:MGI:3695876\|PMID:17189825